| 1 | R. Werkley Duncan | M.D. | 1823-1836 |
| 2 | E. Lodge | B.A. | 1842-1844 |
| 3 | J. Middleton | F.G.S., F.C.S. | 1844-1858 |
| 4 | T.B. Kane | — | 1858-1859 |
| 5 | W. Anderson | LL.D. | 1859-1862 |
| 6 | C. Peirson | M.A. | 1862-1864 |
| 7 | K. Dytton | B.A. | 1864-1882 |
| 8 | A. Thomson | I.C.S. | 1882-1901 |
| 9 | T.C. Jones | B.A. | 1901-1925 |
| 10 | A.J. Fieldon | M.A. | 1925-1937 |
| 11 | H. Croll | B.A., M.Sc. | 1937-1945 |
| 12 | Dr. Karamchand Mehta | M.Sc., Ph.D., F.N.I. | 1945-1950 |
| 13 | Dr. Nihalkaran Sethi | M.Sc., Ph.D., D.Sc. | 1950-1954 |
| 14 | Dr. Harnarayan Singh | M.A., Ph.D. | 1954-1960 |
| 15 | Dr. Manohar Ray | M.Sc., Ph.D., D.Sc., F.N.I., F.N.A.Sc. | 1960-1970 |
| 16 | Dr. Shaligram Sinha | M.Sc., Ph.D., F.N.A.Sc. | 1970-1973 |
| 17 | Dr. Satyanarayan Dubey | M.A., Ph.D. | 1973-1977 |
| 18 | Dr. Rajeshwar Prasad Verma | M.A., Ph.D. | 1977-1979 (Officiating Principal) |
| 19 | Dr. Suraj Narayan Srivastava | M.Sc., Ph.D., D.Sc. | 1979-1982 |
| 20 | Dr. Rajeshwar Prasad Verma | M.A., Ph.D. | 1982-1984 (Substitute Principal) |
| 21 | Dr. Gokul Chandra Sharma | M.A., Ph.D. | 1984-1985 (Substitute Principal) |
| 22 | Dr. Mukhtar Singh | M.Sc., Ph.D., D.Sc., F.E.C.S.I. | 1985 (Substitute Principal) |
| 23 | Dr. Suraj Narayan Srivastava | M.Sc., Ph.D., D.Sc. | 1985-1990 |
| 24 | Dr. Mukhtar Singh | M.Sc., Ph.D., D.Sc., F.E.C.S.I. | July, 1990-2001 |
| 25 | Dr. Rajkumari Sharma | M.Sc., Ph.D., F.A.Z. | Jul.,2001-Nov.,2002(Officiating Principal) |
| 26 | Dr. Ashok Vikram Singh | M.Sc., Ph.D. | 1 Dec., 2002 - 8 Dec., 2002 (Officiating Principal) |
| 27 | Dr. Santosh Kumar | M.Sc., Ph.D. | 9 Dec., 2002 - 6 Jun., 2003 (Officiating Principal) |
| 28 | Dr. Krishna Manohar Garg | M.Sc., Ph.D. | 7 Jun., 2003 - 16 Jun., 2003 (Officiating Principal) |
| 29 | Dr. Ashok Vikram Singh | M.Sc., Ph.D. | 17 Jun., 2003 - 6 Mar., 2008 (Officiating Principal) |
| 30 | Dr. Anil Kumar Johari | M.Sc., Ph.D. | 17 Jun., 2003 - 6 Mar., 2008 (Officiating Principal) |
| 31 | Dr. Umesh Chandra Sharma | M.Sc., Ph.D. | 2 Jul., 2008 - 16 Jan., 2009 (Officiating Principal) |
| 32 | Dr. Manoj Kumar Rawat | M.Sc., Ph.D. | 17 Jan., 2009 - 10 Aug., 2016 |
| 33 | Mr. Narendra Singh | — | 12 Aug., 2016 - 20 Mar., 2017 (Officiating Principal) |
| 34 | Dr. Anil Kumar Gupta | M.Sc., Ph.D. | 21 Mar., 2017 - 14 Dec., 2018 (Officiating Principal) |
| 35 | Dr. Vinod Kumar Maheshwari | M.A., Ph.D., D.Lit. | 14 Dec 2018 - 25 July 2020 |
| 36 | Dr. Rekha Patsariya | Ph.D. | 26 July 2020 - 27 September 2020 |
| 37 | Dr. S. K. Mishra | Ph.D. | 28 September 2020 - 2021 |
| 38 | Dr. C. K. Gautam | Ph.D. | Present |